Hydrogen peroxide participates in perception and transduction of cold stress signal in synechocystis
The double mutant ΔkatG/tpx of cyanobacterium Synechocystis sp. strain PCC 6803, defective in the anti-oxidative enzymes catalase (KatG) and thioredoxin peroxidase (Tpx), is unable to grow in the presence of exogenous H2O2. The ΔkatG/tpx mutant is shown to be extremely sensitive to very low concentrations of H2O2, especially when intensified with cold stress. Analysis of gene expression in both wild-type and ΔkatG/tpx mutant cells treated by combined cold/oxidative stress revealed that H2O2 participates in regulation of expression of cold-responsive genes, affecting either signal perception or transduction. The central role of a transmembrane stress-sensing histidine kinase Hik33 in the cold/oxidative signal transduction pathway is discussed.
Plant and Cell Physiology
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Fedurayev, Pavel V.; Mironov, Kirill S.; Gabrielyan, David A.; Bedbenov, Vladimir S.; Zorina, Anna A.; Shumskaya, Maria; and Los, Dmitry A., "Hydrogen peroxide participates in perception and transduction of cold stress signal in synechocystis" (2018). Kean Publications. 1490.