Therapeutic advantages of cannabimimetic plants: Can they substitute medical cannabis?

Document Type

Article

Publication Date

3-7-2023

Abstract

Cannabis has been used by humans both for recreational and therapeutic purposes since ancient times. Among 113 different cannabinoids from Cannabis, D9-trans-tetrahydrocannabinol (D9THCs) is primarily hallucinogenic and cannabidiol (CBD) is therapeutic. The growing interest in therapeutic uses of Cannabis has created interest in several other plants which are non-cannabinoid and have secondary metabolites similar to CBD known as cannabimimetic plants. The cannabimimetic plants are currently gaining attention and can be the potential alternative to Cannabis because of certain secondary metabolites with a similar mechanism of action binding with cannabinoid receptors. For example, phytoextracts from liverworts Radula marginata, amorfrutin in Amorpha fruticose and several Rhododendron species have been reported to have cannabinoid-like properties. This chapter is providing a complete review of cannabimimetic plants focusing on botanical, biochemical, and potential therapeutic aspects.

Publication Title

Medical Cannabis and the Effects of Cannabinoids on Fighting Cancer, Multiple Sclerosis, Epilepsy, Parkinson's, and Other Neurodegenerative Diseases

First Page Number

259

Last Page Number

273

DOI

10.4018/978-1-6684-5652-1.ch011

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