A method for de novo nucleic acid diagnostic target discovery

Document Type

Article

Publication Date

2-27-2014

Abstract

Motivation: A proper target or marker is essential in any diagnosis (e.g. an infection or cancer). An ideal diagnostic target should be both conserved in and unique to the pathogen. Currently, these targets can only be identified manually, which is time-consuming and usually error-prone. Because of the increasingly frequent occurrences of emerging epidemics and multidrug-resistant 'superbugs', a rapid diagnostic target identification process is needed.

Publication Title

Bioinformatics

First Page Number

3174

Last Page Number

3180

DOI

10.1093/bioinformatics/btu515

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