Effects of colchicine and trimethoxybenzene on glucose oxidation in isolated brown fat cells from rats

Document Type

Article

Publication Date

1-1-1979

Abstract

1. 1. Glucose oxidation in isolated brown fat cells from rats is reduced in the presence of colchicine. 2. 2. The effect of colchicine is seen in the absence or presence of insulin and with or without calcium in the incubation medium. 3. 3. Trimethoxybenzene is as effective as colchicine in reducing glucose oxidation in control and insulin treated fat cells. 4. 4. The ability of colchicine to reduce glucose oxidation in fat cells most likely is independent of the cytoplasmic microtubular system. © 1979.

Publication Title

General Pharmacology

First Page Number

47

Last Page Number

49

DOI

10.1016/0306-3623(79)90028-4

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