Infectivity titers of adenovirus type 5 suspensions after exposure to cigarette smoke

Document Type

Article

Publication Date

1-1-1978

Abstract

Suspensions of adenovirus type 5 in 2.0 ml of cell culture fluid at 37° C were subjected to smoke from four cigarettes over a 4-h period. The cigarettes were smoked in a normal manner, and the inhaled smoke was exhaled through glass tubing into the virus-containing fluid. The virus suspensions were then titrated, using monolayer cultures of HEp-2 cells. Smoke from filter-tipped or regular cigarettes caused a 2- to 3-log drop in titer of tissue culture infectious doses of adenovirus type 5 per 0.1 ml of virus suspension. No reductions in titers were observed with parallel suspensions of the virus subjected to normal inhaled and exhaled air.

Publication Title

Applied and Environmental Microbiology

First Page Number

774

Last Page Number

775

DOI

10.1128/aem.36.5.774-775.1978

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