Glucose uptake and lactic acid production of adenovirus type 5 infected HEp 2 cells cultured under exponential growth and stationary phase conditions

Document Type

Article

Publication Date

12-1-1977

Abstract

Exponentially growing HEp-2 cells have a higher rate of glucose uptake and lactic acid production than stationary phase cells. Infection of cells with adenovirus type 5 stimulates glycolysis irrespective of the original rate of the host cells. Therefore, infected cells cultured under exponential growth conditions have a higher rate of glycolysis than infected stationary phase cells. The rate of host cell glycolysis does not influence the time required for virus replication, the yield of infectious virus particles produced, or the time of appearance and progression of virus induced cytopathology.

Publication Title

Microbios

First Page Number

139

Last Page Number

144

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